Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603218 | 0.87 | MAPT (0.32) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8603934 | 0.82 | MAPT (0.33) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8603141 | 0.81 | CA1 (0.36) | MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7795442 | 0.79 | GAA (0.36) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8601703 | 0.79 | CYP1A2 (0.33) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8598592 | 0.79 | — | — | |
| SCHEMBL8600179 | 0.77 | ESR1 (0.41) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8602224 | 0.76 | ALDH1A1 (0.39) | LMNAMAPT | |
| SCHEMBL8600582 | 0.76 | POLB (0.34) | MAPT | |
| SCHEMBL8602520 | 0.75 | CUL4A (0.33) | LMNAMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |