Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | CES1 | P23141 | 1/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.59 |
| ▸ | FEN1 | P39748 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200893 | 0.84 | CYP3A4 (0.73) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| SCHEMBL1271165 | 0.84 | KMT2A (0.73) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.83 | MEN1 (1.00) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.83 | MEN1 (1.00) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| Dibenzoylmethane SCHEMBL39582 | 0.83 | MEN1 (1.00) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| SCHEMBL7043064 | 0.83 | NR4A2 (0.63) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| SCHEMBL25667317 | 0.82 | KMT2A (0.70) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| Dibenzoylmethane SCHEMBL1628627 | 0.80 | MEN1 (0.94) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| Dibenzoylmethane SCHEMBL6249492 | 0.80 | MEN1 (0.94) | CYP3A4MAPTTDP1KMT2AMEN1 | |
| Dibenzoylmethane SCHEMBL531257 | 0.80 | MEN1 (0.94) | CYP3A4MAPTTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548680-B1 | Beta-oxo-beta-benzenepropanethioamide derivatives | MITSUBISHI CHEM CORP (JP) | 1998-02-25 | — | — | EP | claimed |
| US-5332833-A | Potassium channel modulator, hypotensive, hypersensitive colon syndrome, asthma, enteritis | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-26 | — | — | US | claimed |
| EP-0548680-A1 | Beta-oxo-beta-benzenepropanethioamide derivatives | Mitsubishi Chemical Corporation (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0548680-B1 | Beta-oxo-beta-benzenepropanethioamide derivatives | MITSUBISHI CHEM CORP (JP) | 1998-02-25 | — | — | EP | disclosed |
| EP-0548680-B1 | Beta-oxo-beta-benzenepropanethioamide derivatives | MITSUBISHI CHEM CORP (JP) | 1998-02-25 | — | — | EP | disclosed |
| US-5677444-A | Method for the preparation of β-ketothioamide compound | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1997-10-14 | — | — | US | disclosed |
| WO-1996022086-A1 | MEDICINE CONTAINING β-OXO-β-BENZENEPROPANE-THIOAMIDE DERIVATIVE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-07-25 | — | — | WO | disclosed |
| US-5439927-A | For potassium channel opening, hypotensive agents, broncho- or vasodilators, gastrointestinal disorders | MITSUBISHI KASEI CORPORATION (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5439927-A | For potassium channel opening, hypotensive agents, broncho- or vasodilators, gastrointestinal disorders | MITSUBISHI KASEI CORPORATION (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5332833-A | Potassium channel modulator, hypotensive, hypersensitive colon syndrome, asthma, enteritis | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5332833-A | Potassium channel modulator, hypotensive, hypersensitive colon syndrome, asthma, enteritis | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5332833-A | Potassium channel modulator, hypotensive, hypersensitive colon syndrome, asthma, enteritis | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0548680-A1 | Beta-oxo-beta-benzenepropanethioamide derivatives | Mitsubishi Chemical Corporation (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0548680-A1 | Beta-oxo-beta-benzenepropanethioamide derivatives | Mitsubishi Chemical Corporation (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0548680-A1 | Beta-oxo-beta-benzenepropanethioamide derivatives | Mitsubishi Chemical Corporation (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0314026-B1 | PARTICLE AGENT FOR THE SELECTIVE REMOVAL OF METAL CATIONS FROM AQUEOUS SOLUTIONS, PROCESS FOR ITS PRODUCTION AND ITS USE | Solvay Umweltchemie GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |
| US-5015448-A | Particulate material suitable for selectively separating metal cations from aqueous solutions, process for its production, and use thereof | GUTEC GESELLSCHAFT ZUR ENTWICKLUNG VON UMWELTSCHUTZTECHNOLOGIE MBH (DE) | 1991-05-14 | — | — | US | disclosed |
| EP-0314026-A1 | Particle agent for the selective removal of metal cations from aqueous solutions, process for its production and its use | Solvay Umweltchemie GmbH (DE) | 1989-05-03 | — | — | EP | disclosed |
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |
| US-3931269-A | ANTIINFLAMMATORY | WILLIAM H. RORER, INC. (US) | 1976-01-06 | — | — | US | disclosed |