Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641821 | 0.80 | POLB (0.54) | RAB9ANPC1SMN1; SMN2POLBHPGD | |
| SCHEMBL6639377 | 0.78 | DAO (0.47) | HTR2AHTR2CHTR2BDAORAB9A | |
| SCHEMBL8569773 | 0.77 | DAO (0.34) | HTR2AHTR2CHTR2BDAORAB9A | |
| SCHEMBL6636642 | 0.75 | DAO (0.47) | DAORAB9ANPC1SMN1; SMN2CA12 | |
| SCHEMBL6639145 | 0.75 | CYP1A2 (0.48) | DAORAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL8125458 | 0.74 | HSP90AA1 (0.44) | HTR2AHTR2CHTR2BDAORAB9A | |
| SCHEMBL6643920 | 0.73 | RAB9A (0.56) | DAORAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL6635668 | 0.73 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2CA12CA1 | |
| SCHEMBL8125405 | 0.72 | HSP90AA1 (0.44) | HTR2AHTR2CHTR2BDAORAB9A | |
| SCHEMBL8569771 | 0.71 | DAO (0.34) | DAORAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |