SCHEMBL8599402

SCHEMBL8599402

CC(C)(CN)N(C(=O)O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.44
MEN1 O00255 3/20 0.44
CYP2C19 P33261 2/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
GLA P06280 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
MAPT P10636 1/20 0.37
RIPK1 Q13546 2/20 0.37
ADRA2C P18825 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 2/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7034982 0.78 KMT2A (0.47) KMT2AMEN1CYP2C19CYP3A4CYP2C9
SCHEMBL5712822 0.75 KMT2A (0.44) KMT2AMEN1CYP2C19CYP3A4CYP2C9
SCHEMBL11016845 0.73 KMT2A (0.44) KMT2AMEN1CYP2C19CYP3A4CYP2C9
SCHEMBL20163753 0.73 MEN1 (0.53) KMT2AMEN1ALDH1A1TSHRRIPK1
SCHEMBL7540362 0.72 KMT2A (0.42) KMT2AMEN1CYP2C19CYP3A4CYP2C9
SCHEMBL9435677 0.71 KMT2A (0.45) KMT2AMEN1CYP2C19CYP3A4CYP2C9
SCHEMBL9629093 0.70 ALDH1A1 (0.44) KMT2AMEN1CYP2C19CYP3A4CYP2C9
SCHEMBL6037525 0.70 KMT2A (0.41) KMT2AMEN1CYP2C19CYP3A4CYP2C9
SCHEMBL10959895 0.70 NPSR1 (0.50) KMT2AMEN1CYP2C19CYP3A4CYP2C9
SCHEMBL1008397 0.70 NPSR1 (0.44) KMT2AMEN1CYP2C19CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0804525-A4 DIMERCAPTOTHIADIAZOLE-MERCAPTAN COUPLED COMPOUNDS AS MULTIFUNCTIONAL ADDITIVES FOR LUBRICANTS AND FUELS MOBIL OIL CORP (US) 1998-09-02 EP disclosed
EP-0804525-A1 DIMERCAPTOTHIADIAZOLE-MERCAPTAN COUPLED COMPOUNDS AS MULTIFUNCTIONAL ADDITIVES FOR LUBRICANTS AND FUELS MOBIL OIL CORPORATION (US) 1997-11-05 EP disclosed
WO-1996006903-A1 DIMERCAPTOTHIADIAZOLE-MERCAPTAN COUPLED COMPOUNDS AS MULTIFUNCTIONAL ADDITIVES FOR LUBRICANTS AND FUELS MOBIL OIL CORPORATION (US) 1996-03-07 WO disclosed