Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599522 | 1.00 | PTGIR (0.48) | PTGIRCA1CA2ACHEPTGDR2 | |
| SCHEMBL8600077 | 0.84 | PTGIR (0.52) | PTGIRCA1CA2ACHEPTGDR2 | |
| SCHEMBL8626475 | 0.83 | PTGIR (0.57) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL8626228 | 0.83 | PTGIR (0.57) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL10357606 | 0.83 | PTGIR (0.52) | PTGIRCA1CA2ACHEPTGDR2 | |
| SCHEMBL14211188 | 0.80 | PTGDR2 (0.52) | PTGIRCA1CA2ACHEPTGDR2 | |
| SCHEMBL1842695 | 0.79 | CYP1A2 (0.50) | PTGIRCA1CA2ACHEPTGDR2 | |
| SCHEMBL8602826 | 0.78 | PTGIR (0.50) | PTGIRCA1CA2ACHEHSP90AA1 | |
| SCHEMBL8602824 | 0.78 | PTGIR (0.50) | PTGIRCA1CA2ACHEHSP90AA1 | |
| SCHEMBL10357228 | 0.78 | CYP1A2 (0.48) | PTGIRCA1CA2ACHEPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |