Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626228 | 1.00 | PTGIR (0.57) | PTGIRTBXAS1GAASIGMAR1PTGDR2 | |
| SCHEMBL8626755 | 0.86 | PTGIR (0.42) | PTGIRGAASIGMAR1ALDH1A1MAPT | |
| SCHEMBL8599522 | 0.83 | PTGIR (0.48) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8599525 | 0.83 | PTGIR (0.48) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8626753 | 0.82 | GAA (0.44) | PTGIRGAASIGMAR1ALDH1A1MAPT | |
| SCHEMBL9155513 | 0.78 | PTGIR (0.69) | PTGIRTBXAS1SIGMAR1PTGDR2KDM4C | |
| SCHEMBL9155480 | 0.77 | PTGIR (0.68) | PTGIRTBXAS1SIGMAR1PTGDR2KDM4C | |
| SCHEMBL10554252 | 0.76 | PTGIR (0.58) | PTGIRTBXAS1PTGDR2ALDH1A1KDM4C | |
| SCHEMBL8858587 | 0.76 | PTGIR (0.72) | PTGIRTBXAS1SIGMAR1PTGDR2 | |
| SCHEMBL9050868 | 0.74 | PTGIR (0.64) | PTGIRTBXAS1PTGDR2ALDH1A1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |