Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | C1R | P00736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599781 | 0.81 | KMT2A (0.42) | MEN1KMT2AHTTTSHRMAPK1 | |
| SCHEMBL8596917 | 0.79 | KMT2A (0.43) | MEN1KMT2AHTTTSHRMAPK1 | |
| SCHEMBL8628924 | 0.79 | PIM1 (0.37) | MEN1KMT2ATSHRMAPK1PIM1 | |
| SCHEMBL8600738 | 0.79 | MEN1 (0.40) | MEN1KMT2AHTTTSHRMAPK1 | |
| SCHEMBL8598709 | 0.78 | KMT2A (0.40) | MEN1KMT2ATSHRMAPK1PIM1 | |
| SCHEMBL8596309 | 0.76 | MEN1 (0.38) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL8562084 | 0.75 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1PIM1 | |
| SCHEMBL8566957 | 0.75 | MAPT (0.46) | MEN1KMT2ATSHRMAPK1PIM1 | |
| SCHEMBL8596283 | 0.74 | MEN1 (0.37) | MEN1KMT2AHTTTSHRMAPK1 | |
| SCHEMBL8596304 | 0.74 | MAPT (0.38) | MEN1KMT2AHTTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |