Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562084 | 0.85 | MEN1 (0.44) | MAPTTDP1POLBKMT2AMAPK1 | |
| SCHEMBL8563233 | 0.80 | ALDH1A1 (0.52) | MAPTTDP1POLBKMT2AMAPK1 | |
| SCHEMBL8599781 | 0.78 | KMT2A (0.42) | MAPTTDP1POLBKMT2AMAPK1 | |
| SCHEMBL8561151 | 0.78 | BACE1 (0.51) | MAPTTDP1POLBKMT2AMAPK1 | |
| SCHEMBL8561794 | 0.77 | VCAM1 (0.57) | MAPTPOLBKMT2AMAPK1CTSB | |
| SCHEMBL8561585 | 0.77 | PIN1 (0.41) | MAPTTDP1POLBKMT2AMAPK1 | |
| SCHEMBL8600014 | 0.76 | TXNRD1 (0.49) | MAPTKMT2AMAPK1CYP1A2MEN1 | |
| SCHEMBL16833053 | 0.76 | GRM2 (0.41) | MAPTTDP1POLBKMT2AKDM4E | |
| SCHEMBL3298254 | 0.76 | KMT2A (0.54) | MAPTTDP1POLBKMT2AMAPK1 | |
| SCHEMBL8599530 | 0.75 | MEN1 (0.41) | MAPTTDP1POLBKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |