Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 9/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SOD1 | P00441 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466371 | 0.84 | MAOB (0.59) | APPHRH3NPC1RAB9AMAOB | |
| SCHEMBL6292403 | 0.84 | APP (0.67) | APPNPC1RAB9AKMT2AMAOB | |
| SCHEMBL6014765 | 0.84 | APP (0.67) | APPNPC1RAB9AKMT2AMAOB | |
| SCHEMBL13929692 | 0.82 | MAOB (0.61) | RXRARXRBAPPTDP1L3MBTL1 | |
| SCHEMBL15336496 | 0.82 | MAOB (0.61) | RXRARXRBAPPTDP1L3MBTL1 | |
| SCHEMBL464352 | 0.82 | RXRA (0.66) | RXRARXRBAPPL3MBTL1NPC1 | |
| SCHEMBL13977985 | 0.82 | APP (0.69) | RXRARXRBAPPNPC1RAB9A | |
| SCHEMBL8272576 | 0.82 | RXRA (0.66) | RXRARXRBAPPTDP1L3MBTL1 | |
| SCHEMBL13952163 | 0.82 | APP (0.69) | RXRARXRBAPPNPC1RAB9A | |
| SCHEMBL24629212 | 0.80 | RXRA (0.59) | RXRARXRBAPPTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100463917-C | Reductive alkylation of glycopeptide antibiotics | LILLY CO ELI (US) | 2009-02-25 | — | — | CN | disclosed |
| CN-1244802-A | Reductive alkylation of glycopeptide antibiotics | LILLY CO ELI (US) | 2000-02-16 | — | — | CN | disclosed |
| WO-1998021952-A1 | REDUCING AGENT FOR REDUCTIVE ALKYLATION OF GLYCOPEPTIDE ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |