SCHEMBL8599598

SCHEMBL8599598

CC=CCSc1cc(N)c(F)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8600375 1.00 MEN1 (0.36) MEN1KMT2A
SCHEMBL8599597 1.00 MEN1 (0.36) MEN1KMT2A
SCHEMBL8603017 0.81 NPC1 (0.31) MEN1KMT2A
SCHEMBL8603129 0.78 SLC6A4 (0.33)
SCHEMBL8601382 0.76 KMT2A (0.39) KMT2A
SCHEMBL8601210 0.75
SCHEMBL8602607 0.75
SCHEMBL8878138 0.74 PTGS2 (0.38)
SCHEMBL8598215 0.74 GAA (0.35) MEN1KMT2A
SCHEMBL8633135 0.73 TLR8 (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626370-B1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL CO (JP) 1998-02-11 EP disclosed
EP-0626370-A1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1994-11-30 EP disclosed