SCHEMBL8599672

SCHEMBL8599672

O=C(O)CC(C(=O)O)C1CO1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
FOLH1 Q04609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3070889 0.77
SCHEMBL3070892 0.77
SCHEMBL3068352 0.77
SCHEMBL3062278 0.77
SCHEMBL3068358 0.77
SCHEMBL27909276 0.77 LMNA (0.51) CYP1A2TSHRLMNAMEN1HTT
SCHEMBL18528957 0.75 FOLH1 (0.38) TSHRLMNASLC22A6FOLH1
SCHEMBL10379796 0.74 CHRM1 (0.43) TDP1SMN1; SMN2
SCHEMBL9654862 0.74 CPA1 (0.55) LMNAMEN1KMT2AFOLH1
SCHEMBL18302820 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770711-A DERIVATIZED WITH 2,3-EPOXYSUCCINIC ACID, 1,2-EPOXYPROPANE-1,2,3-TRICARBOXYLIC ACID, AND OR 2-(EPOXYETHYL)SUCCINIC ACID; CROSSLINKING KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-06-23 US claimed
US-5770711-A DERIVATIZED WITH 2,3-EPOXYSUCCINIC ACID, 1,2-EPOXYPROPANE-1,2,3-TRICARBOXYLIC ACID, AND OR 2-(EPOXYETHYL)SUCCINIC ACID; CROSSLINKING KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-06-23 US disclosed
US-5770711-A DERIVATIZED WITH 2,3-EPOXYSUCCINIC ACID, 1,2-EPOXYPROPANE-1,2,3-TRICARBOXYLIC ACID, AND OR 2-(EPOXYETHYL)SUCCINIC ACID; CROSSLINKING KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-06-23 US disclosed