SCHEMBL8599735

SCHEMBL8599735

CCCCCCCCCCCCCCCCCC(=O)NC[C@H]1CC[C@H](C(=O)O)CC1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.58
CNR2 P34972 11/20 0.50
CNR1 P21554 10/20 0.50
GBA1 P04062 1/20 0.46
HSP90AA1 P07900 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8595923 1.00 FAAH (0.58) FAAHCNR2CNR1GBA1HSP90AA1
SCHEMBL8596053 1.00 FAAH (0.58) FAAHCNR2CNR1GBA1HSP90AA1
SCHEMBL22870141 1.00 FAAH (0.58) FAAHCNR2CNR1GBA1HSP90AA1
SCHEMBL8596047 1.00 FAAH (0.58) FAAHCNR2CNR1GBA1HSP90AA1
SCHEMBL8599738 1.00 FAAH (0.58) FAAHCNR2CNR1GBA1HSP90AA1
SCHEMBL8595918 1.00 FAAH (0.58) FAAHCNR2CNR1GBA1HSP90AA1
SCHEMBL8599036 0.98 FAAH (0.59) FAAHCNR2CNR1GBA1
SCHEMBL8599031 0.98 FAAH (0.59) FAAHCNR2CNR1GBA1
SCHEMBL8595463 0.94 FAAH (0.57) FAAHCNR2CNR1
SCHEMBL8595466 0.94 FAAH (0.57) FAAHCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585130-B1 External preparation for skin containing a depigmentation agent SHISEIDO CO LTD (JP) 1998-01-28 EP disclosed
US-5690914-A TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION SHISEIDO CO., LTD (JP) 1997-11-25 US disclosed
EP-0585130-A2 External preparation for skin containing a depigmentation agent SHISEIDO COMPANY LIMITED (JP) 1994-03-02 EP disclosed