Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.65 |
| ▸ | PDE4A | P27815 | 2/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602152 | 0.86 | SLC22A12 (0.78) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1553843 | 0.86 | PDE4A (0.67) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8604805 | 0.85 | SLC22A12 (0.74) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8599806 | 0.85 | PDE4A (0.66) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8572873 | 0.84 | SLC22A12 (0.70) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8599802 | 0.83 | PDE4A (0.67) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600343 | 0.82 | SLC22A12 (0.67) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8599076 | 0.81 | SLC22A12 (0.65) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1554169 | 0.81 | PDE4A (0.65) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16587422 | 0.79 | SLC22A12 (0.70) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |