Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 13/20 | 0.78 |
| ▸ | PDE4A | P27815 | 3/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604805 | 0.91 | SLC22A12 (0.74) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8572873 | 0.90 | SLC22A12 (0.70) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11976690 | 0.88 | SLC22A12 (1.00) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600343 | 0.87 | SLC22A12 (0.67) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11975001 | 0.87 | SLC22A12 (1.00) | SLC22A12 | |
| SCHEMBL11977167 | 0.86 | SLC22A12 (1.00) | SLC22A12 | |
| SCHEMBL8599076 | 0.86 | SLC22A12 (0.65) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8599807 | 0.86 | SLC22A12 (0.65) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11976676 | 0.85 | SLC22A12 (0.73) | SLC22A12ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8602713 | 0.85 | SLC22A12 (0.63) | SLC22A12PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |