Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | TTPA | P49638 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 9/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358821 | 0.88 | MEN1 (0.52) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL11709896 | 0.88 | MEN1 (0.52) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL11358826 | 0.88 | MEN1 (0.52) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7560788 | 0.85 | MEN1 (0.36) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8601542 | 0.84 | TTPA (0.42) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8599270 | 0.84 | TTPA (0.42) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8599266 | 0.84 | TTPA (0.42) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL13592375 | 0.82 | MEN1 (0.48) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL19899579 | 0.78 | MEN1 (0.42) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8599804 | 0.78 | MEN1 (0.53) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345593-B2 | 2-substituted coumaran derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-4978761-A | Enzyme inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-12-18 | — | — | US | disclosed |
| EP-0345593-A1 | 2-substituted coumaran derivatives | Takeda Chemical Industries, Ltd. (JP) | 1989-12-13 | — | — | EP | disclosed |