Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807678 | 1.00 | LMNA (0.30) | LMNATSHRKDM4EMAPT | |
| SCHEMBL8031590 | 1.00 | LMNA (0.30) | LMNATSHRKDM4EMAPT | |
| SCHEMBL10778430 | 1.00 | LMNA (0.30) | LMNATSHRKDM4EMAPT | |
| SCHEMBL8035929 | 0.85 | — | — | |
| SCHEMBL181178 | 0.69 | SCN1A (0.41) | LMNATSHRKDM4EMAPT | |
| SCHEMBL2993610 | 0.69 | SCN1A (0.41) | LMNATSHRKDM4EMAPT | |
| SCHEMBL4697737 | 0.69 | SCN1A (0.41) | LMNATSHRKDM4EMAPT | |
| SCHEMBL4655278 | 0.69 | SCN1A (0.41) | LMNATSHRKDM4EMAPT | |
| SCHEMBL8852722 | 0.69 | LMNA (0.32) | LMNATSHRKDM4EMAPT | |
| SCHEMBL5409875 | 0.69 | LMNA (0.32) | LMNATSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823893-A1 | NOVEL TETRACYCLINE DERIVATIVES | PFIZER INC. (US) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034852-A1 | NOVEL TETRACYCLINE DERIVATIVES | PFIZER, INC. (US) | 1996-11-07 | — | — | WO | disclosed |