⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38539 | 0.69 | — | — | |
| SCHEMBL969805 | 0.67 | NOS2 (0.32) | — | |
| SCHEMBL1515054 | 0.67 | — | — | |
| SCHEMBL970472 | 0.67 | — | — | |
| SCHEMBL1515017 | 0.67 | — | — | |
| SCHEMBL1515119 | 0.67 | — | — | |
| SCHEMBL1323028 | 0.67 | — | — | |
| SCHEMBL1515260 | 0.67 | — | — | |
| SCHEMBL152044 | 0.67 | — | — | |
| SCHEMBL446963 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1945 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| US-11851433-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2023-12-26 | — | — | US | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| EP-3625234-B1 | HEXAHYDROPYRAZOLO [1,2-A] DIAZEPINONES AND RELATED HETEROCYCLES AS INHIBITORS OF RIP-1 KINASE | DENALI THERAPEUTICS INC (US) | 2023-09-20 | — | — | EP | claimed |
| CN-113004278-B | Bicyclic heterocycles as FGFR inhibitors | 因赛特控股公司 | 2023-07-21 | — | — | CN | claimed |
| US-20230112172-A1 | SUBSTITUED AMINO-PYRIMIDINES | HOFFMANN-LA ROCHE INC. (US) | 2023-04-13 | — | — | US | claimed |
| EP-4161918-A1 | SUBSTITUTED AMINO-PYRIMIDINES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | claimed |
| US-20230096602-A1 | TETRAHYDROCYCLOPENTA[B]INDOLE COMPOUNDS FOR TREATMENT OF RENAL DISEASE | EIRGEN PHARMA LTD. (IE) | 2023-03-30 | — | — | US | claimed |
| CN-115551844-A | Substituted amino-pyrimidines | 豪夫迈·罗氏有限公司 | 2022-12-30 | — | — | CN | claimed |
| EP-4096660-A1 | TETRAHYDROCYCLOPENTA[B]INDOLE COMPOUNDS FOR THE TREATMENT OF RENAL DISEASE | EirGen Pharma Ltd. (IE) | 2022-12-07 | — | — | EP | claimed |
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | claimed |
| US-5616456-A | CONTAINIG A MEROCYANINE DYE; HIGH SENSITIVITY, CONTRAST, AND GOOD STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1997-04-01 | — | — | US | claimed |
| WO-1996035678-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-14 | — | — | WO | claimed |
| CN-1134697-A | Pyrimidine-sulfanyl and alkyl ether compounds | UPJOHN CO (US) | 1996-10-30 | — | — | CN | claimed |
| EP-0728130-A1 | PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013267-A1 | PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS | THE UPJOHN COMPANY (US) | 1995-05-18 | — | — | WO | claimed |
| US-5385920-A | Anticholesterol or antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-01-31 | — | — | US | claimed |
| EP-0574312-A1 | Diacylglycerol nicotinates, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-12-15 | — | — | EP | claimed |
| EP-0192976-B1 | COMPOUNDS HAVING ANTIHYPERLIPEMIC ACTIVITY, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1989-06-14 | — | — | EP | claimed |
| EP-0192976-A1 | Compounds having antihyperlipemic activity, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1986-09-03 | — | — | EP | claimed |