Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602052 | 0.91 | KDM4E (0.41) | ALDH1A1KDM4EHSD17B10MAPTCA12 | |
| SCHEMBL8601740 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MAPTCA12 | |
| SCHEMBL8603481 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10MAPTCA12 | |
| SCHEMBL8604539 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8604561 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10BACE1KMT2A | |
| SCHEMBL8602030 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10MAPTGAA | |
| SCHEMBL8603459 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8604553 | 0.68 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8603718 | 0.68 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8600124 | 0.67 | MAPT (0.39) | ALDH1A1KDM4EMAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |