Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880295 | 0.91 | NPC1 (0.39) | ALDH1A1HPGDMAPK1TRIM24TYR | |
| SCHEMBL4444924 | 0.88 | NPC1 (0.45) | ALDH1A1HPGDCYP3A4MAPTNPC1 | |
| SCHEMBL29382372 | 0.88 | NPC1 (0.45) | ALDH1A1HPGDCYP3A4MAPTNPC1 | |
| SCHEMBL30887099 | 0.87 | KMT2A (0.36) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL10892218 | 0.87 | KMT2A (0.36) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL4453092 | 0.86 | ELANE (0.43) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL9862749 | 0.81 | NPC1 (0.38) | ALDH1A1HPGDMAPK1MAPTNPC1 | |
| SCHEMBL4439833 | 0.81 | NPC1 (0.54) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL21630098 | 0.81 | MAPT (0.40) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL28682239 | 0.81 | POLB (0.37) | MAPK1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714134-A | SUNSCREEN AGENTS | SOCIETE L'OREAL S.A. (FR) | 1998-02-03 | — | — | US | disclosed |
| EP-0711779-B1 | Sunscreens, cosmetic sunscreen compositions and uses thereof | OREAL (FR) | 1998-01-28 | — | — | EP | disclosed |
| US-5610257-A | SUNSCREENS | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |
| EP-0711779-A1 | Sunscreens, cosmetic sunscreen compositions and uses thereof | L'OREAL (FR) | 1996-05-15 | — | — | EP | disclosed |