SCHEMBL4444924

SCHEMBL4444924

C=C(C)C(=O)Oc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.45
RAB9A P51151 7/20 0.45
ALDH1A1 P00352 4/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
ELANE P08246 1/20 0.45
LMNA P02545 1/20 0.43
IGF2BP2 Q9Y6M1 1/20 0.40
KMT2A Q03164 3/20 0.39
ATM Q13315 1/20 0.39
MAPT P10636 6/20 0.39
KDM4E B2RXH2 4/20 0.39
HPGD P15428 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
POLB P06746 3/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382372 1.00 NPC1 (0.45) NPC1RAB9AALDH1A1SMN1; SMN2ELANE
SCHEMBL29384504 0.90 NPC1 (0.52) NPC1RAB9AALDH1A1SMN1; SMN2ELANE
SCHEMBL93326 0.90 NPC1 (0.52) NPC1RAB9AALDH1A1SMN1; SMN2ELANE
SCHEMBL8600147 0.88 ALDH1A1 (0.39) NPC1RAB9AALDH1A1SMN1; SMN2ELANE
SCHEMBL4453092 0.88 ELANE (0.43) NPC1RAB9AALDH1A1SMN1; SMN2ELANE
SCHEMBL10892218 0.87 KMT2A (0.36) NPC1RAB9AALDH1A1SMN1; SMN2ELANE
SCHEMBL30887099 0.87 KMT2A (0.36) NPC1RAB9AALDH1A1SMN1; SMN2ELANE
SCHEMBL29992530 0.84 NPC1 (0.41) NPC1RAB9AALDH1A1SMN1; SMN2ELANE
SCHEMBL11376140 0.83 POLB (0.41) NPC1RAB9AALDH1A1SMN1; SMN2LMNA
SCHEMBL30887096 0.83 NPC1 (0.36) NPC1RAB9AALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114058142-B Transparent fluorine-containing polymer film 浙江省化工研究院有限公司 2023-05-12 CN claimed
CN-114058142-A Transparent fluorine-containing polymer film 浙江省化工研究院有限公司 2022-02-18 CN claimed
CN-112574438-B Preparation method and application of perovskite quantum dot polymer microsphere with core-shell structure 昆山博益鑫成高分子材料有限公司 2021-05-11 CN claimed
CN-112574438-A Preparation method and application of perovskite quantum dot polymer microsphere with core-shell structure 昆山博益鑫成高分子材料有限公司 2021-03-30 CN claimed
CN-109351213-B Polyvinylidene fluoride composite membrane containing modified polydopamine nanoparticles and preparation method thereof 中国科学院长春应用化学研究所 2020-07-28 CN claimed
CN-108047383-B Preparation method of polyvinylidene fluoride copolymer 中国科学院长春应用化学研究所 2020-03-17 CN claimed
EP-0080663-B1 VINYLIDENE FLUORIDE RESIN-BASED SHAPED PRODUCT KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-07-23 EP claimed
US-4413095-A Vinylidene fluoride resin-based shaped product KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-11-01 US claimed
EP-0080663-A2 Vinylidene fluoride resin-based shaped product KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-06-08 EP claimed
CN-114058142-B Transparent fluorine-containing polymer film 浙江省化工研究院有限公司 2023-05-12 CN disclosed
WO-2022179456-A1 PREPARATION METHOD AND APPLICATION OF PEROVSKITE QUANTUM DOT POLYMER MICROSPHERE HAVING CORE-SHELL STRUCTURE 昆山博益鑫成高分子材料有限公司 2022-09-01 WO disclosed
CN-114058142-A Transparent fluorine-containing polymer film 浙江省化工研究院有限公司 2022-02-18 CN disclosed
CN-112574438-B Preparation method and application of perovskite quantum dot polymer microsphere with core-shell structure 昆山博益鑫成高分子材料有限公司 2021-05-11 CN disclosed
CN-112574438-A Preparation method and application of perovskite quantum dot polymer microsphere with core-shell structure 昆山博益鑫成高分子材料有限公司 2021-03-30 CN disclosed
EP-0407932-B1 UV light-absorbing skin-protecting composition SHIONOGI & CO (JP) 1995-05-24 EP disclosed
US-5063048-A Acrylic ester or amide polymers SHIONOGI & CO., LTD. (JP) 1991-11-05 US disclosed
EP-0407932-A2 UV light-absorbing skin-protecting composition SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1991-01-16 EP disclosed
EP-0080663-B1 VINYLIDENE FLUORIDE RESIN-BASED SHAPED PRODUCT KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-07-23 EP disclosed
US-4413095-A Vinylidene fluoride resin-based shaped product KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-11-01 US disclosed
EP-0080663-A2 Vinylidene fluoride resin-based shaped product KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-06-08 EP disclosed