Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.76 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553375 | 0.87 | PDE4A (0.67) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11977182 | 0.86 | SLC22A12 (1.00) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8601429 | 0.86 | PDE4A (0.66) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601425 | 0.83 | PDE4A (0.69) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1554280 | 0.82 | PDE4A (0.64) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8602152 | 0.81 | SLC22A12 (0.78) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8604805 | 0.80 | SLC22A12 (0.74) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8572873 | 0.79 | SLC22A12 (0.70) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3944098 | 0.78 | CYP3A4 (0.75) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL29642680 | 0.78 | CYP3A4 (0.75) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |