SCHEMBL8600246

SCHEMBL8600246

N=c1oc(C2CC2)cn1-c1cccc(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
HTT P42858 2/20 0.40
HTR2C P28335 2/20 0.40
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
HTR1D P28221 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
KCNH2 Q12809 1/20 0.39
NOTUM Q6P988 3/20 0.39
HTR2A P28223 1/20 0.39
HTR2B P41595 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
CYP17A1 P05093 1/20 0.38
POLB P06746 1/20 0.38
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8569284 0.79 HTT (0.44) ALDH1A1HTTHTR2CHTR3EHTR3B
SCHEMBL8570049 0.75 HTT (0.41) ALDH1A1HTTHTR2CHTR3EHTR3B
SCHEMBL29985028 0.66 CYP17A1 (0.45) ALDH1A1HTR2CHTR3EHTR3BHTR1D
SCHEMBL4861038 0.65 HTT (0.44) ALDH1A1HTTHTR2CHTR3EHTR3B
SCHEMBL15766297 0.64 DDB1 (0.64) ALDH1A1HTTHTR2CHTR3EHTR3B
SCHEMBL8010810 0.64 HTT (0.41) ALDH1A1HTTHTR2CHTR3EHTR3B
SCHEMBL8424346 0.64 HTT (0.43) ALDH1A1HTTHTR2CHTR3EHTR3B
SCHEMBL8428297 0.64 HTT (0.43) ALDH1A1HTTHTR2CHTR3EHTR3B
SCHEMBL8423759 0.64 HTT (0.43) ALDH1A1HTTHTR2CHTR3EHTR3B
Hydrochloric Acid SCHEMBL4852356 0.64 HTT (0.43) ALDH1A1HTTHTR2CHTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998000408-A1 N-PHENYLIMINO HETEROCYCLIC DERIVATIVES AND THEIR USE AS HERBICIDES NOVARTIS AG (CH) 1998-01-08 WO disclosed