Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.41 |
| ▸ | SCN2B | O60939 | 2/20 | 0.41 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570049 | 0.83 | HTT (0.41) | HTTALDH1A1EPHX2HTR3EHTR3B | |
| SCHEMBL8600246 | 0.79 | ALDH1A1 (0.40) | HTTALDH1A1EPHX2HTR3EHTR3B | |
| SCHEMBL8570767 | 0.76 | NOTUM (0.45) | HTTCYP1A2EPHX2NOTUMSCN2B | |
| SCHEMBL8570769 | 0.76 | NOTUM (0.45) | HTTCYP1A2EPHX2NOTUMSCN2B | |
| SCHEMBL4861038 | 0.76 | HTT (0.44) | HTTALDH1A1CYP1A2EPHX2HTR3E | |
| Hydrochloric Acid SCHEMBL4852356 | 0.75 | HTT (0.43) | HTTALDH1A1CYP1A2EPHX2HTR3E | |
| SCHEMBL8428297 | 0.75 | HTT (0.43) | HTTALDH1A1CYP1A2EPHX2HTR3E | |
| Hydrochloric Acid SCHEMBL7971305 | 0.74 | HTT (0.43) | HTTALDH1A1CYP1A2EPHX2HTR3E | |
| SCHEMBL8010810 | 0.71 | HTT (0.41) | HTTALDH1A1EPHX2HTR3EHTR3B | |
| SCHEMBL29875573 | 0.70 | CYP1A2 (0.63) | HTTALDH1A1CYP1A2NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000408-A1 | N-PHENYLIMINO HETEROCYCLIC DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1998-01-08 | — | — | WO | disclosed |