Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600854 | 0.88 | CYP1A2 (0.34) | ADRA2AADRA2BADRA2C | |
| SCHEMBL8598378 | 0.86 | PTAFR (0.33) | PTAFRGABRA1GABRB2CNR2 | |
| SCHEMBL8601873 | 0.84 | HDAC1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL8601974 | 0.84 | — | — | |
| SCHEMBL8600729 | 0.83 | KDM4E (0.32) | PTAFR | |
| SCHEMBL8597697 | 0.82 | CYP2D6 (0.35) | PTAFR | |
| SCHEMBL8602905 | 0.81 | PTAFR (0.37) | PTAFRGABRA1GABRB2CNR2 | |
| SCHEMBL8599873 | 0.80 | CHRNB2 (0.33) | — | |
| SCHEMBL8603734 | 0.79 | PIK3CD (0.31) | GABRA1GABRB2ADRA2AADRA2BADRA2C | |
| SCHEMBL8603587 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |