Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.44 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.44 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599113 | 1.00 | USP2 (0.56) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL8600393 | 1.00 | USP2 (0.56) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL8598749 | 1.00 | USP2 (0.56) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL8598288 | 1.00 | USP2 (0.56) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL8599077 | 0.98 | USP2 (0.53) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL8596436 | 0.92 | USP2 (0.46) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL8597882 | 0.84 | HSD17B10 (0.54) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL9847324 | 0.80 | TSHR (0.39) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL9412145 | 0.80 | CETP (0.34) | USP2CES2HTTPLA2G2CSPHK1 | |
| SCHEMBL28692169 | 0.80 | HSD17B10 (0.50) | USP2CES2HTTPLA2G2CSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592669-B1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5665270-A | Optically active trifluorolactic acid derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0592669-A1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5204020-A | For display elements or an electrooptical element | SHOWA SHELL SEKIYU K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| EP-0327349-A2 | Liquid crystal compounds | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1989-08-09 | — | — | EP | disclosed |