Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596436 | 0.87 | USP2 (0.46) | TSHRCES2HTTUSP2PLA2G2C | |
| SCHEMBL8599077 | 0.82 | USP2 (0.53) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL8600393 | 0.80 | USP2 (0.56) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL8598749 | 0.80 | USP2 (0.56) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL8598288 | 0.80 | USP2 (0.56) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL8599113 | 0.80 | USP2 (0.56) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL8600399 | 0.80 | USP2 (0.56) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL28692169 | 0.80 | HSD17B10 (0.50) | CES2HTTMEN1KMT2AMAPT | |
| SCHEMBL7750651 | 0.78 | TSHR (0.45) | TSHRCES2HTTMEN1THRB | |
| SCHEMBL14534599 | 0.78 | TSHR (0.45) | TSHRCES2HTTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419283-A2 | Azlactone-functional silicon containing compounds and derivatives thereof | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-03-27 | — | — | EP | disclosed |