Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | CALML3 | P27482 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | SDHA | P31040 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938119 | 0.88 | MAOA (0.56) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL3328441 | 0.86 | MAOA (0.76) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL3328443 | 0.86 | MAOA (0.76) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL7947049 | 0.85 | MAOA (0.68) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL27820541 | 0.85 | MAOA (0.64) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL4750476 | 0.85 | MAOA (0.58) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL6649952 | 0.84 | MAOA (0.66) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL3762420 | 0.84 | MAOA (0.57) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL3755864 | 0.84 | MAOA (0.57) | MAOAMAOBCALML3PTGS1SDHA | |
| SCHEMBL13054622 | 0.84 | MAOA (0.57) | MAOAMAOBCALML3PTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801246-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1998-09-01 | — | — | US | claimed |
| EP-0610265-B1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 1996-12-27 | — | — | EP | claimed |
| WO-1993009103-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |