Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096424 | 0.87 | IDO1 (0.50) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL31504492 | 0.87 | IDO1 (0.50) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL10409093 | 0.75 | MAPT (0.53) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL5886509 | 0.75 | PTPRC (0.49) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL5886239 | 0.75 | PTPRC (0.53) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL30496126 | 0.75 | MAPT (0.53) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL5886422 | 0.75 | PTPRC (0.49) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL13445016 | 0.75 | PTPRC (0.49) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL27921312 | 0.72 | PTPRC (0.46) | PTPRCMAPTPTPN1MEN1KMT2A | |
| SCHEMBL7899015 | 0.72 | PTPRC (0.46) | PTPRCMAPTPTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876368-A1 | USE OF MONO- OR DIKETONE TETRACYCLIC DERIVATIVES, RESULTING NOVEL COMPOUNDS AND THERAPEUTICAL USE THEREOF | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1998-11-11 | — | — | EP | claimed |
| WO-1997021709-A1 | USE OF MONO- OR DIKETONE TETRACYCLIC DERIVATIVES, RESULTING NOVEL COMPOUNDS AND THERAPEUTICAL USE THEREOF | LABORATOIRE INNOTHERA (FR) | 1997-06-19 | — | — | WO | claimed |
| EP-0876368-A1 | USE OF MONO- OR DIKETONE TETRACYCLIC DERIVATIVES, RESULTING NOVEL COMPOUNDS AND THERAPEUTICAL USE THEREOF | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997021709-A1 | USE OF MONO- OR DIKETONE TETRACYCLIC DERIVATIVES, RESULTING NOVEL COMPOUNDS AND THERAPEUTICAL USE THEREOF | LABORATOIRE INNOTHERA (FR) | 1997-06-19 | — | — | WO | disclosed |