Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886239 | 0.72 | PTPRC (0.53) | PTPRCMEN1KMT2ATHRBIDO1 | |
| SCHEMBL10409093 | 0.72 | MAPT (0.53) | PTPRCMEN1KMT2ATHRBIDO1 | |
| SCHEMBL13445016 | 0.72 | PTPRC (0.49) | PTPRCMEN1KMT2ATHRBIDO1 | |
| SCHEMBL7900917 | 0.72 | CDC25B (0.53) | MEN1KMT2ATHRBIDO1ALDH1A1 | |
| SCHEMBL5886422 | 0.72 | PTPRC (0.49) | PTPRCMEN1KMT2ATHRBIDO1 | |
| SCHEMBL30496126 | 0.72 | MAPT (0.53) | PTPRCMEN1KMT2ATHRBIDO1 | |
| SCHEMBL8600436 | 0.72 | PTPRC (0.49) | PTPRCMEN1KMT2ATHRBIDO1 | |
| SCHEMBL5886509 | 0.72 | PTPRC (0.49) | PTPRCMEN1KMT2ATHRBIDO1 | |
| SCHEMBL27921312 | 0.69 | PTPRC (0.46) | PTPRCMEN1KMT2ATHRBIDO1 | |
| SCHEMBL9700287 | 0.69 | KMT2A (0.48) | MEN1KMT2ATHRBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265220-B1 | NON-IMMUNOCHEMICAL METHOD BY REACTING A COMPOUND COMPRISING CIS-1,4-DIOXO-2-BUTENE MOIETY OR HYDROLYTICALLY DERIVED PRECURSOR WITH HOMOCYSTEINE, THEN DETECTING PRODUCT WITHOUT SEPARATION FROM LIQUID | ULLMAN EDWIN F (US) | 2001-07-24 | — | — | US | claimed |
| WO-2000000821-A1 | ASSAY FOR HOMOCYSTEINE | ULLMAN EDWIN F (US) | 2000-01-06 | — | — | WO | claimed |