Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 7/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600538 | 1.00 | CDA (0.47) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6424353 | 0.76 | CDA (0.45) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6674416 | 0.75 | CDA (0.47) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL20833069 | 0.75 | CDA (0.47) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6906558 | 0.75 | LMNA (0.45) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL4214653 | 0.75 | LMNA (0.49) | LMNASMN1; SMN2DNMT1BLMPMP22 | |
| SCHEMBL3630509 | 0.75 | LMNA (0.45) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL4214655 | 0.75 | LMNA (0.49) | LMNASMN1; SMN2DNMT1BLMPMP22 | |
| SCHEMBL23240639 | 0.74 | CDA (0.67) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL3498860 | 0.74 | CDA (0.67) | CDASLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715613-B1 | NEW DIPHENYLHEXENE | PECHAN REINHARD (DE) | 1998-01-28 | — | — | EP | disclosed |
| US-5650445-A | Diphenylhexene composition for use in treating liver carcinoma and psoriasis | PECHAN REINHARD (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5578742-A | INHIBIT UNCONTROLLED CELL PROLIFERATION, TREATMENT OF PSORIASIS, AIDS, CANCER, ANTITUMOR | METZLER MANFRED (DE) | 1996-11-26 | — | — | US | disclosed |
| EP-0636115-B1 | NOVEL BIS-PHENYL-HEXENES | METZLER MANFRED (DE) | 1996-08-14 | — | — | EP | disclosed |
| EP-0715613-A1 | NEW DIPHENYLHEXENE | PECHAN, Reinhard (DE) | 1996-06-12 | — | — | EP | disclosed |
| WO-1995006020-A1 | NEW DIPHENYLHEXENE | PECHAN REINHARD (DE) | 1995-03-02 | — | — | WO | disclosed |
| EP-0636115-A1 | NOVEL BIS-PHENYL-HEXENES. | METZLER MANFRED (DE) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993022262-A1 | NOVEL BIS-PHENYL-HEXENES | METZLER MANFRED (DE) | 1993-11-11 | — | — | WO | disclosed |