Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | HTR6 | P50406 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601386 | 0.89 | AKR1C3 (0.64) | MEN1KMT2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL2886421 | 0.84 | KMT2A (1.00) | MEN1KMT2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL27958054 | 0.83 | MEN1 (0.83) | MEN1KMT2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL6285571 | 0.80 | HTR6 (0.55) | MEN1KMT2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL6285576 | 0.80 | HTR6 (0.55) | MEN1KMT2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL4815832 | 0.78 | HTR6 (0.75) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6284042 | 0.77 | HTR6 (0.53) | MEN1KMT2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL6281043 | 0.77 | HTR6 (0.51) | MEN1KMT2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL6284046 | 0.77 | HTR6 (0.53) | MEN1KMT2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL6281048 | 0.77 | HTR6 (0.51) | MEN1KMT2AHTR6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728712-A | 3,4-disubstituted-phenylsulphonamides and their therapeutic use | CHIROSCIENCE LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |