SCHEMBL8600740

SCHEMBL8600740

CCCCC(CC)CNC(=O)CCC(=O)NCC(CC)CCCC

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
CA2 P00918 2/20 0.52
HTT P42858 2/20 0.50
GLA P06280 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
ATM Q13315 1/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
MAPK1 P28482 1/20 0.47
TP53 P04637 1/20 0.46
FAAH O00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11663143 0.94 TSHR (0.53) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL14836356 0.94 TSHR (0.53) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL8600737 0.93 TSHR (0.48) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL28673768 0.93 FAAH (0.53) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL28345202 0.91 FAAH (0.56) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL8029825 0.91 FAAH (0.56) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL19125886 0.91 FAAH (0.56) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL16312317 0.90 TSHR (0.57) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL8601998 0.90 TSHR (0.47) TSHRALDH1A1CYP3A4CA2HTT
SCHEMBL31138113 0.90 TSHR (0.49) TSHRALDH1A1CYP3A4CA2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5798331-A AGROCHEMICAL FORMULATIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-08-25 US disclosed
US-4207285-A LOW-FOAM BASF AKTIENGESELLSCHAFT (DE) 1980-06-10 US disclosed