Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100096 | 0.82 | TDP1 (0.71) | TDP1KDM4EPOLBL3MBTL1CYP2C9 | |
| SCHEMBL1133466 | 0.82 | TDP1 (0.66) | TDP1KDM4EPOLBL3MBTL1CYP2C9 | |
| SCHEMBL763265 | 0.82 | TDP1 (0.66) | TDP1KDM4EPOLBL3MBTL1CYP2C9 | |
| SCHEMBL16659214 | 0.82 | TDP1 (0.57) | TDP1KDM4EPOLBL3MBTL1CYP2C9 | |
| SCHEMBL30939614 | 0.82 | CYP2C9 (0.54) | TDP1KDM4EPOLBL3MBTL1CYP2C9 | |
| SCHEMBL15546777 | 0.82 | CYP2C9 (0.54) | TDP1KDM4EPOLBL3MBTL1CYP2C9 | |
| SCHEMBL3520528 | 0.81 | L3MBTL1 (0.66) | TDP1POLBL3MBTL1CYP2C9NPC1 | |
| SCHEMBL23279388 | 0.81 | CYP1A2 (0.69) | TDP1POLBL3MBTL1CYP2C9NPC1 | |
| SCHEMBL15547312 | 0.79 | CYP1A2 (0.58) | TDP1KDM4EPOLBL3MBTL1CYP2C9 | |
| SCHEMBL5905952 | 0.78 | CYP1A2 (0.69) | TDP1KDM4EPOLBL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767275-A | Preparation of triazolone compounds | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1998-06-16 | — | — | US | disclosed |
| EP-0668857-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLONE COMPOUNDS | ACRAF (IT) | 1998-02-25 | — | — | EP | disclosed |