Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.55 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596983 | 0.86 | KMT2A (0.49) | ANPEPENPEPKMT2APLGPLAT | |
| Hydrochloric Acid SCHEMBL8600687 | 0.84 | KMT2A (0.48) | ANPEPENPEPKMT2APLGPLAT | |
| SCHEMBL8597479 | 0.84 | KMT2A (0.48) | ANPEPENPEPKMT2APLGPLAT | |
| SCHEMBL8597687 | 0.83 | KMT2A (0.47) | ANPEPENPEPKMT2APLGPLAT | |
| SCHEMBL8601004 | 0.82 | KMT2A (0.52) | ANPEPENPEPKMT2APLGPLAT | |
| SCHEMBL8596548 | 0.82 | KMT2A (0.46) | ANPEPENPEPKMT2APLGPLAT | |
| SCHEMBL8596277 | 0.81 | KMT2A (0.57) | ANPEPENPEPKMT2APLGPLAT | |
| SCHEMBL8599837 | 0.81 | KMT2A (0.45) | ANPEPENPEPKMT2APLGPLAT | |
| SCHEMBL8598904 | 0.81 | KMT2A (0.45) | ANPEPENPEPKMT2APLGPLAT | |
| SCHEMBL8595700 | 0.80 | KMT2A (0.47) | ANPEPENPEPKMT2APLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |