Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596548 | 0.90 | KMT2A (0.46) | KMT2ABLMTDP1LMNAPLG | |
| SCHEMBL8597687 | 0.85 | KMT2A (0.47) | KMT2ATDP1LMNAPLGPLAT | |
| SCHEMBL8598904 | 0.83 | KMT2A (0.45) | KMT2ATDP1LMNAPLGPLAT | |
| SCHEMBL8596983 | 0.82 | KMT2A (0.49) | KMT2ATDP1LMNAPLGPLAT | |
| SCHEMBL8595700 | 0.82 | KMT2A (0.47) | KMT2ALMNAPLGPLATANPEP | |
| SCHEMBL13151574 | 0.81 | ALOX15 (0.43) | KMT2ABLMALOX15PMP22TDP1 | |
| SCHEMBL16103641 | 0.81 | ALOX15 (0.43) | KMT2ABLMALOX15PMP22TDP1 | |
| SCHEMBL8597479 | 0.81 | KMT2A (0.48) | KMT2ATDP1LMNAPLGPLAT | |
| SCHEMBL8600964 | 0.81 | ANPEP (0.55) | KMT2ATDP1LMNAPLGPLAT | |
| Hydrochloric Acid SCHEMBL8600687 | 0.81 | KMT2A (0.48) | KMT2ATDP1LMNAPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |