Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 5/20 | 0.54 |
| ▸ | FNTB | P49356 | 5/20 | 0.54 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8763367 | 0.99 | OPRK1 (0.56) | OPRK1MMEANPEPFNTAFNTB | |
| SCHEMBL11685692 | 0.91 | MME (0.68) | MMEANPEPFNTAFNTBPGGT1B | |
| SCHEMBL8213011 | 0.90 | MME (0.59) | OPRK1MMEANPEPFNTAFNTB | |
| Hydrochloric Acid SCHEMBL11681328 | 0.90 | MME (0.67) | MMEANPEPFNTAFNTBPGGT1B | |
| SCHEMBL9510846 | 0.89 | FNTA (0.66) | FNTAFNTBPGGT1BKMT2ALTA4H | |
| SCHEMBL2544520 | 0.89 | FNTA (0.66) | FNTAFNTBPGGT1BKMT2ALTA4H | |
| SCHEMBL13093207 | 0.89 | FNTA (0.66) | FNTAFNTBPGGT1BKMT2ALTA4H | |
| SCHEMBL4765841 | 0.89 | FNTA (0.66) | FNTAFNTBPGGT1BKMT2ALTA4H | |
| SCHEMBL30051273 | 0.86 | FNTA (0.63) | FNTAFNTBPGGT1BKMT2ALTA4H | |
| Hydrochloric Acid SCHEMBL11234310 | 0.86 | KMT2A (0.57) | MMEANPEPFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840918-A | PEPTIDOMIMETIC COMPOUNDS USEFUL IN THE TREATMENT OF RAS-ASSOCIATED HUMAN CANCERS | EISAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0750609-A4 | ISOPRENYL TRANSFERASE INHIBITORS | EISAI CO LTD (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0750609-A1 | ISOPRENYL TRANSFERASE INHIBITORS | Eisai Co., Ltd. (JP) | 1997-01-02 | — | — | EP | disclosed |