Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5964780 | 0.67 | CYP1A2 (0.50) | CA12CA1CA2CA9CYP1A2 | |
| SCHEMBL21574005 | 0.62 | CA12 (0.38) | CA12CA1CA2CA9CYP1A2 | |
| SCHEMBL65000 | 0.62 | CYP1A2 (0.53) | CA12CA1CA2CA9CYP1A2 | |
| Hydrochloric Acid SCHEMBL27423371 | 0.62 | CA12 (0.33) | CA12CA1CA2CA9CYP1A2 | |
| Hydrochloric Acid SCHEMBL8599323 | 0.62 | CA12 (0.33) | CA12CA1CA2CA9CYP1A2 | |
| Hydrochloric Acid SCHEMBL8600072 | 0.62 | CA12 (0.33) | CA12CA1CA2CA9CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL24170 | 0.60 | — | — | |
| Ammonia Solution, Strong SCHEMBL4222522 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL822288 | 0.60 | CA12 (0.32) | CA12CA1CA2CA9CYP1A2 | |
| SCHEMBL5139662 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571945-B1 | Catalyst for copolymerizing ethylene with alpha-olefin and process for producing ethylene-alpha-olefin copolymer using the catalyst | SUMITOMO CHEMICAL CO (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5508364-A | USING A ZIELGER CATALYST CONTAINING A TITANIUM COMPOUND WITH TITANIUM NITROGEN BOND, ORGANOMAGNESIUM AND ORGANOALUMINUM COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0571945-A2 | Catalyst for copolymerizing ethylene with alpha-olefin and process for producing ethylene-alpha-olefin copolymer using the catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-12-01 | — | — | EP | disclosed |