Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150182 | 0.93 | CYP3A4 (0.34) | CETPCYP3A4 | |
| SCHEMBL2150530 | 0.87 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL11030099 | 0.86 | SMPD1 (0.42) | SMPD1LPAR3LPAR2LPAR1 | |
| SCHEMBL29291760 | 0.83 | TSHR (0.39) | CYP3A4 | |
| SCHEMBL2149759 | 0.83 | — | — | |
| SCHEMBL956338 | 0.79 | TSHR (0.35) | CETPSIRT2 | |
| SCHEMBL29039981 | 0.79 | TSHR (0.35) | CETPSIRT2 | |
| SCHEMBL2150185 | 0.79 | SMPD1 (0.37) | SMPD1CETPLPAR3LPAR2LPAR1 | |
| SCHEMBL2149661 | 0.79 | SMPD1 (0.33) | SMPD1CETPLPAR3LPAR2LPAR1 | |
| SCHEMBL13078128 | 0.77 | TSHR (0.33) | CETPSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599251-B1 | Use in viscous coupling of a fluid comprising a polyorganosiloxane and a viscosity inhibitor | COSMO OIL CO LTD (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0599251-A1 | Fluid composition for use in viscous coupling | COSMO OIL COMPANY, LTD (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-4425223-A | AN ORGANIC PHOSPHITE OR PHOSPHATE ESTER AND A SULFONIC ACID | ATLANTIC RICHFIELD COMPANY (US) | 1984-01-10 | — | — | US | disclosed |