Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 3/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8599772 | 0.99 | MEN1 (0.39) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| SCHEMBL8600057 | 0.92 | MEN1 (0.39) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| SCHEMBL8603836 | 0.92 | MEN1 (0.40) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8599756 | 0.91 | MEN1 (0.40) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| SCHEMBL8602358 | 0.90 | CYP3A4 (0.38) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| SCHEMBL8601824 | 0.90 | KMT2A (0.41) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| SCHEMBL8600560 | 0.90 | MEN1 (0.44) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8599724 | 0.89 | KMT2A (0.40) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| SCHEMBL8604410 | 0.88 | MEN1 (0.37) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8603573 | 0.88 | MEN1 (0.44) | MEN1CYP2D6CYP2C19KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763458-A | NERVOUS SYSTEM DISORDERS, ANXIETY, ANTIDEPRESSANTS AND COGNITION ACTIVATORS | SYNTEX (U.S.A.) INC. (US) | 1998-06-09 | — | — | US | disclosed |