Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570238 | 0.82 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601691 | 0.82 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600858 | 0.82 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8604475 | 0.82 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600848 | 0.81 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8605556 | 0.80 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600404 | 0.80 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8605746 | 0.79 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8598411 | 0.79 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8599046 | 0.79 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | claimed |