Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604475 | 0.98 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8570238 | 0.91 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600858 | 0.87 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600404 | 0.85 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8600848 | 0.85 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8605556 | 0.84 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8598411 | 0.83 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8599046 | 0.83 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601278 | 0.82 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8604316 | 0.82 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | claimed |
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |