Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679135 | 0.84 | LMNA (0.55) | SMN1; SMN2ALDH1A1KMT2AHTTHPGD | |
| SCHEMBL25392022 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL22506679 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL22506677 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL2543476 | 0.83 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL3545215 | 0.80 | S1PR1 (0.48) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL26127761 | 0.78 | MEN1 (0.59) | ALDH1A1KMT2AMEN1TDP1MAPT | |
| SCHEMBL2305794 | 0.78 | MEN1 (0.59) | ALDH1A1KMT2AMEN1TDP1MAPT | |
| SCHEMBL5784665 | 0.77 | MEN1 (0.64) | KMT2AMEN1TDP1MAPTL3MBTL1 | |
| SCHEMBL24609344 | 0.75 | NPC1 (0.79) | SMN1; SMN2ALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733928-A | IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-03-31 | — | — | US | disclosed |