SCHEMBL8601330

SCHEMBL8601330

CC1(N(C(=O)Nc2ccc3ncccc3c2)C2CCCCCC2)CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.50
POLB P06746 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 1/20 0.50
CCNE1 P24864 1/20 0.48
CDK2 P24941 1/20 0.48
CDK5 Q00535 1/20 0.48
RAB9A P51151 6/20 0.46
PABPC1 P11940 1/20 0.46
HTT P42858 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
EPHX2 P34913 1/20 0.43
NOTUM Q6P988 1/20 0.42
OTUD7B Q6GQQ9 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8601443 0.78 RAB9A (0.48) NPC1POLBMEN1KMT2AMAPT
SCHEMBL7762686 0.77 NPC1 (0.52) NPC1POLBMEN1KMT2AMAPT
SCHEMBL8605647 0.77 EPHX1 (0.52) NPC1POLBMEN1KMT2AMAPT
SCHEMBL8603355 0.77 EPHX1 (0.52) NPC1POLBMEN1KMT2AMAPT
SCHEMBL8636134 0.77 EPHX1 (0.52) NPC1POLBMEN1KMT2AMAPT
SCHEMBL8601811 0.77 EPHX1 (0.52) NPC1POLBMEN1KMT2AMAPT
SCHEMBL8603993 0.77 ATM (0.47) NPC1POLBMEN1KMT2AMAPT
SCHEMBL8605923 0.76 RAB9A (0.47) NPC1POLBMEN1KMT2AMAPT
SCHEMBL8604411 0.75 RAB9A (0.54) NPC1POLBMEN1KMT2AMAPT
SCHEMBL8603779 0.75 RAB9A (0.54) NPC1POLBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5733931-A ANTICHOLESTEROL AGENTS NISSIN FOOD PRODUCTS CO., LTD. (JP) 1998-03-31 US disclosed