Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597477 | 0.93 | ALDH1A1 (0.46) | HTTL3MBTL1PTGESSMN1; SMN2LMNA | |
| SCHEMBL8596881 | 0.87 | POLB (0.43) | HTTL3MBTL1PTGESSMN1; SMN2TSHR | |
| SCHEMBL8595623 | 0.87 | TYK2 (0.41) | HTTPTGESSMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8601764 | 0.86 | POLB (0.43) | HTTL3MBTL1PTGESSMN1; SMN2TSHR | |
| SCHEMBL8599983 | 0.86 | TYK2 (0.40) | HTTPTGESSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8598065 | 0.86 | TYK2 (0.40) | HTTPTGESSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8596911 | 0.83 | TP53 (0.39) | HTTL3MBTL1PTGESSMN1; SMN2KMT2A | |
| SCHEMBL8600023 | 0.83 | ALDH1A1 (0.41) | HTTL3MBTL1PTGESSMN1; SMN2TSHR | |
| SCHEMBL8596612 | 0.83 | MEN1 (0.41) | HTTPTGESSMN1; SMN2LMNATSHR | |
| SCHEMBL8597312 | 0.83 | TP53 (0.43) | HTTL3MBTL1PTGESSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |