Methane

Methane

SCHEMBL8601392

C.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.65
HPGD P15428 1/20 0.65
ALOX15 P16050 1/20 0.65
ALOX12 P18054 1/20 0.65
CASP1 P29466 1/20 0.65
HSD17B10 Q99714 1/20 0.65
MAOA P21397 4/20 0.63
MAOB P27338 3/20 0.63
TDP1 Q9NUW8 2/20 0.61
TAAR1 Q96RJ0 2/20 0.61
CYP2A6 P11509 1/20 0.61
HTR2A P28223 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
LOXL2 Q9Y4K0 1/20 0.61
KCNH2 Q12809 1/20 0.57
CALM1 P0DP23 1/20 0.56
FFAR1 O14842 1/20 0.55
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
SIGMAR1 Q99720 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9741303 0.96 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL62125 0.96 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
Benzene SCHEMBL3440179 0.96 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL11747668 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
Iodide SCHEMBL9705905 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL25403475 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
Hydrogen Sulfide SCHEMBL5468201 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL55138 0.92 MAOB (0.72) ALDH1A1HPGDALOX15ALOX12CASP1
Hydrogen Sulfide SCHEMBL7592179 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL742615 0.92 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US claimed
CN-113966271-A Agent capable of reacting with or removing oxygen molecules 李蓁蓁 2022-01-21 CN disclosed
CN-101467935-A Cosmetic and dermatological formulations including isononyl benzoate EVONIK GOLDSCHMIDT GMBH (DE) 2009-07-01 CN disclosed
CN-1964695-A Topical l-carnitine compositions LONZA AG (US) 2007-05-16 CN disclosed
CN-1200670-C Composition, specially the cosmetics compositions, having copolymer connected with at least one fluorescent brightener OREAL (FR) 2005-05-11 CN disclosed
CN-1177829-C Substituted sulphonyl cyanamides, method for the production thereof and their use as medicaments ���ĵ�˹ҩ��¹����޹�˾ 2004-12-01 CN disclosed
CN-1339960-A Cosmetic compositions for photoprotection the skin/or hair containing benzotriazole derivative and triazine bis-resorcinyl OREAL (FR) 2002-03-13 CN disclosed
CN-1073110-C Process for the preparation of biphenyl derivatives AMERICAN HOME PROD (US) 2001-10-17 CN disclosed
CN-1305463-A Substituted sulphonyl cyanamides, method for the production thereof and their use as medicaments AVENTIS PHARMA GMBH (DE) 2001-07-25 CN disclosed
CN-1295830-A Composition, specially the cosmetics compositions, having copolymer connected with at least one fluorescent brightener OREAL (FR) 2001-05-23 CN disclosed
CN-1192214-A Process for the preparation of biphenyl derivatives AMERICAN HOME PROD (US) 1998-09-02 CN disclosed
EP-0653441-B1 Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1998-02-04 EP disclosed
CN-1141444-A Top coats for shoot and run printing plates MINNESOTA MINING & MFG (US) 1997-01-29 CN disclosed
US-4282138-A NONFLAMMABLE ICI AMERICAS INC. (US) 1981-08-04 US disclosed
US-4139577-A USED IN CASTINGS AND REINFORCED LAMINATES ICI AMERICAS INC. (US) 1979-02-13 US disclosed
US-4093601-A Vinyl esters of tetracarboxylic acids and resins derived therefrom ICI AMERICAS INC. (US) 1978-06-06 US disclosed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US disclosed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US disclosed