Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.71 |
| ▸ | PLG | P00747 | 1/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.71 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.71 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.71 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860152 | 0.83 | PRSS1 (1.00) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL851919 | 0.78 | ALDH1A1 (0.56) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL850443 | 0.75 | PRSS1 (0.71) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL30260147 | 0.72 | HPGD (0.69) | HPGDALDH1A1SMN1; SMN2NPC1CYP3A4 | |
| SCHEMBL13302265 | 0.72 | HPGD (0.69) | HPGDALDH1A1SMN1; SMN2NPC1CYP3A4 | |
| SCHEMBL860509 | 0.71 | PRSS1 (0.52) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL851286 | 0.70 | PRSS1 (0.53) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL3791583 | 0.69 | HPGD (0.42) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL851791 | 0.69 | PDE4A (0.43) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL860519 | 0.68 | F2 (0.57) | F2PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |