Phosphine

Phosphine

SCHEMBL8601562

CCCCCCCCCCCCCCCCCC(=O)OCc1ccccc1-c1cccc(C)c1C.P

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.43
CYP4A11 Q02928 2/20 0.43
P2RX7 Q99572 1/20 0.42
POLM Q9NP87 1/20 0.41
POLK Q9UBT6 1/20 0.41
POLL Q9UGP5 1/20 0.41
POLH Q9Y253 1/20 0.41
DGKA P23743 1/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
GAA P10253 1/20 0.40
ELANE P08246 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PAM P19021 2/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9346896 0.99 CYP4F2 (0.44) CYP4F2CYP4A11P2RX7POLMPOLK
Ammonia Solution, Strong SCHEMBL9346925 0.98 CYP4F2 (0.43) CYP4F2CYP4A11P2RX7POLMPOLK
SCHEMBL6669719 0.87 DGKA (0.47) CYP4F2CYP4A11P2RX7DGKAGAA
SCHEMBL10628068 0.84 CYP4F2 (0.51) CYP4F2CYP4A11P2RX7DGKAGAA
SCHEMBL10627972 0.84 CYP4F2 (0.51) CYP4F2CYP4A11P2RX7DGKAGAA
SCHEMBL6665932 0.84 CYP4F2 (0.51) CYP4F2CYP4A11P2RX7DGKAGAA
Ammonia Solution, Strong SCHEMBL10430550 0.83 CYP4F2 (0.50) CYP4F2CYP4A11P2RX7DGKAGAA
SCHEMBL10623418 0.83 CYP4F2 (0.52) CYP4F2CYP4A11P2RX7DGKAGAA
SCHEMBL17938493 0.81 DGKA (0.56) CYP4F2CYP4A11DGKAELANEL3MBTL1
SCHEMBL17938461 0.81 DGKA (0.56) CYP4F2CYP4A11DGKAELANEL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309794-B1 No-post-cure method of curing polyacrylate polymers ZEON CHEMICALS INC (US) 1998-01-28 EP disclosed
EP-0362459-B1 Polyacrylate polymers utilizing substituted urea retarder ZEON CHEMICALS USA INC (US) 1994-08-10 EP disclosed
US-5081194-A Quaternary ammonium or phosphonium curing agent ZEON CHEMICALS U.S.A., INC. (US) 1992-01-14 US disclosed
US-5079304-A Curable ZEON CHEMICALS U.S.A., INC. (US) 1992-01-07 US disclosed
US-5008345-A Two-Part Curing System Containing A Metallic Acid Salt And An Ammonium Or Phosphonium Quaternary Salt ZEON CHEMICAL USA, INC. (US) 1991-04-16 US disclosed