SCHEMBL8601583

SCHEMBL8601583

C=COC(C)=O.CCCCCCCCCCCCCCOC(=O)/C=C/C(=O)OCCCCCCCCCCCCCC

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.63
ATM Q13315 1/20 0.59
TSHR P16473 4/20 0.51
HPGD P15428 1/20 0.51
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
APP P05067 4/20 0.45
NAAA Q02083 1/20 0.44
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508425 1.00 HCAR2 (0.63) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL3306422 1.00 HCAR2 (0.63) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL9508429 1.00 HCAR2 (0.63) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL8601584 1.00 HCAR2 (0.63) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL8526243 1.00 HCAR2 (0.63) HCAR2ATMTSHRHPGDALDH1A1
Ethylene SCHEMBL9829853 0.98 HCAR2 (0.61) HCAR2ATMTSHRHPGDALDH1A1
Stearyl Fumaric Acid SCHEMBL8015800 0.94 HCAR2 (0.74) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL8602279 0.94 HCAR2 (0.74) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL8602281 0.94 HCAR2 (0.74) HCAR2ATMTSHRHPGDALDH1A1
Stearyl Fumaric Acid SCHEMBL8015803 0.94 HCAR2 (0.74) HCAR2ATMTSHRHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0343981-B2 Use of an additive in a fuel oil composition as a flow improver EXXON CHEMICAL PATENTS INC (US) 1998-02-25 EP disclosed
EP-0283293-B2 Use of low temperature flow improvers in distillate oils EXXON CHEMICAL PATENTS INC (US) 1997-01-22 EP disclosed
EP-0306290-B1 Flow improvers and cloud point depressants EXXON CHEMICAL PATENTS INC (US) 1994-01-05 EP disclosed
US-5011505-A Unsaturated diesters having controlled length alkyl groups in homo- or copolymers or blends do not impair flow control agents EXXON CHEMICAL PATENTS INC. (US) 1991-04-30 US disclosed
EP-0343981-A1 Fuel oil compositions EXXON CHEMICAL PATENTS INC. (US) 1989-11-29 EP disclosed
US-4882034-A POLYMER CONTAINING MORE THAN ONE AMIDE GROUP AND DERIVED FROM ALIPHATIC OLEFIN AND MALEIC ANHYDRIDE; FLOW IMPROVER EXXON CHEMICAL PATENTS INC. (US) 1989-11-21 US disclosed
EP-0306290-A1 Flow improvers and cloud point depressants EXXON CHEMICAL PATENTS INC. (US) 1989-03-08 EP disclosed
EP-0283293-A1 Use of low temperature flow improvers in distillate oils EXXON CHEMICAL PATENTS INC. (US) 1988-09-21 EP disclosed