Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603469 | 0.94 | GAA (0.52) | GAAHTTMAPTSLC6A2SLC6A4 | |
| SCHEMBL8603475 | 0.93 | SLC6A2 (0.42) | GAAHTTMAPTSLC6A2SLC6A4 | |
| SCHEMBL8604557 | 0.91 | SLC6A4 (0.45) | GAAHTTSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL8600124 | 0.85 | MAPT (0.39) | GAAHTTMAPTSLC6A2SLC6A4 | |
| SCHEMBL8603715 | 0.83 | SLC6A4 (0.39) | SLC6A2SLC6A4ALDH1A1PSMB5PPARG | |
| SCHEMBL8602990 | 0.81 | GAA (0.44) | GAAHTTMAPTALDH1A1PPARG | |
| SCHEMBL8603616 | 0.80 | SLC6A4 (0.47) | SLC6A2SLC6A4ALDH1A1PSMB5PPARG | |
| SCHEMBL8603483 | 0.79 | GAA (0.43) | GAAHTTMAPTALDH1A1PPARG | |
| SCHEMBL8604548 | 0.78 | MMP8 (0.43) | SLC6A2SLC6A4ALDH1A1PSMB5PPARG | |
| SCHEMBL8603455 | 0.77 | SLC6A4 (0.38) | SLC6A2SLC6A4ALDH1A1PSMB5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |