Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096095 | 0.79 | POLB (0.53) | POLBALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL27004797 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL23581575 | 0.75 | POLB (0.64) | POLBALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL395435 | 0.75 | ALDH1A1 (0.64) | POLBALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL9454925 | 0.75 | ALDH1A1 (0.48) | POLBALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL20856975 | 0.73 | POLB (0.61) | POLBALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL1921414 | 0.73 | ALDH1A1 (0.61) | POLBALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL29505834 | 0.72 | SMN1; SMN2 (0.53) | POLBALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL11873425 | 0.72 | SMN1; SMN2 (0.53) | POLBALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL27834660 | 0.72 | POLB (0.46) | POLBALDH1A1TDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000750-A1 | PROCESS FOR PRODUCING LIQUID CRYSTAL ALIGNMENT LAYER AND LIQUID CRYSTAL DISPLAY DEVICE WITH THE USE OF THE SAME | HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) | 1998-01-08 | — | — | WO | disclosed |